History PRP


Beginning in the 1990s and continuing until now, “growth factors” have been a hot topic in the medical world. It is clear that growth factors play a pivotal role in all types of wound healing. Investigation into the use of PRP has been reported as early as the 1970s, but the necessary equipment was large, expensive ($40,000 in 1996), and required a large quantity of a patients blood (450 cc) and therefore limited to the operating room for large scale surgeries. Starting in the early 1990s, multiple reports and studies in maxillofacial dental, periodontal surgery, cosmetic surgery, and skin grafting showed dramatically improved healing with PRP.

Dollarphotoclub_50652942In the early 2000s, the use of PRP expanded into orthopedics to augment healing in bone grafts and fractures. Success there encouraged its use in sportsDollarphotoclub_50652942 medicine for connective tissue repair. Mishra and Pavelko, associated with Stanford University, published the first human study supporting the use of PRP for chronic tendon problems in 2006. This study reported a 93% reduction in pain at two year follow up. Then, in 2008, Pittsburgh Steelers’ wide receiver, Hines Ward, received PRP for a knee medial collateral ligament sprain, and the Steelers went on to win SuperBowl XLII. Ward credited PRP for his ability to play in that game and his success with this treatment was discussed on national television.

Since then, other high profile athletes – such as Takashi Saito, closing pitcher for the L.A. Dodgers, and golfer Tiger Woods – credit PRP for helping them return to their sport. PRP continues to gain wider acceptance in the sports world with studies continuing to validate the use of PRP for ligament and tendon injuries, knee osteoarthritis, degenerative knee cartilage, chronic elbow tendonosis, muscle strain and tears, jumpers knee, plantar fasciitis and rotator cuff tendinopathy – albeit some skeptics and controversy remains.

healthy-kneesAs the use of PRP has grown, the demand and availability for smaller, more portable and affordable machines has also grown. There are now several available models which allow the physician to create PRP from a small sample of ahealthy-knees patients blood in the office setting. Machines are very affordable and many companies offer a complimentary machine with a minimum purchase of PRP preparation kits over a period of time. However, not all marketed PRP devices are equal; they vary in quantity of blood required, platelet concentration, viability and number of spin cycles. Harvest Technologies was one of the first PRP devices to gain FDA approval. This system uses a floating shelf technology which preserves the viability of platelets until use. In his 2005 text, Marx rated the PReP unit by Harvest Technologies, along with PCCS by Implant Innovations, as the two most effective and practical PRP devices for physician office use, outpatient surgery centers, and wound care center treatment. Since then, other companies have produced additional effective platelet concentrating systems.

Mission Hills Medical Center is the Main Resource for PRP and Stem Cell Treatments

     4954 Van Nuys Blvd., Suite 202, Sherman Oaks, CA 91403

10306 Sepu


Sherman Oaks, CA 91403 Phone:(818) 361-0115